Type 2 Diabetes mellitus treatment intensification and deintensification
Abstract
The prevalence of type 2 diabetes is increasing worldwide, presenting a considerable clinical and public health burden. Existing evidence demonstrates that optimisation of diabetes treatment regimens can reduce the risk of morbidity and disability. This retrospective observational cohort study aimed to identify factors associated with treatment intensification and deintensification in people with type 2 diabetes and evaluate effects of the treatment approaches on clinical outcomes. The cohort included 183 patients enrolled in a primary care Diabetes Medication Therapy Adherence Clinic program in Malaysia between 1 January 2016 and 31 March 2020. Multivariable logistic regression analyses were conducted to determine the clinical or socio-demographic characteristics associated with treatment intensification or deintensification.
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